Parameter estimation of kinetic models from metabolic profiles: two-phase dynamic decoupling method
نویسندگان
چکیده
منابع مشابه
Parameter estimation of kinetic models from metabolic profiles: two-phase dynamic decoupling method
MOTIVATION Time-series measurements of metabolite concentration have become increasingly more common, providing data for building kinetic models of metabolic networks using ordinary differential equations (ODEs). In practice, however, such time-course data are usually incomplete and noisy, and the estimation of kinetic parameters from these data is challenging. Practical limitations due to data...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2011
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btr293